Why is nad+ so important in fermentation

Why is nad+ so important in fermentation1

Fermentation is a complex process, in which NAD+ is very important. Let’s learn why is nad+ so important in the fermentation.

Why is nad+ so important in the fermentation:


The fermentation process could be defined in different ways. If we think in the biochemical field, it breakdown the chemical bonds in sugars and converts into the energy which is not possible to produce in the glycolysis process.

During our normal activities, the amount of oxygen for breathing is enough in our body but when we involve in high activities in our daily life our body cannot supply enough oxygen for body cells, as a result, we breathe faster.

 So, that time how body cells keep cellular respiration function without enough oxygen?

Without oxygen, the glycolysis process can be continued. If oxygen is available, it is used in cellular respiration where oxygen picks up the electrons. But if there is no oxygen electron couldn’t be possible to pick up and this time glycolysis processes can continue by the production of ATP without oxygen.

Why is nad+ so important in fermentation
Figure: Fermentation Process.

ATP molecules are made in the glycolysis process. Nevertheless, the ATP molecules are not made in the fermentation process, but it allows glycolysis to continue. Fermentation can remove the electron from NADH molecules and regenerate NAD+ molecules which is need for glycolysis that picks up the electron where no need oxygen to pick up the electrons for continuing the body function. Glycolysis process would be stopped if there is no electron pick up and without NAD+ it is not possible to pick up the electrons from the splitting of glucose.

How NAD+ can help for continuing the glycolysis process?

When oxygen is not present in the cell, in the glycolysis process, glucose is broken down into two molecules of pyruvate by the production of two molecules of ATP and reduces NAD+ molecule into NADH which is a store of energy.

Then, during the fermentation process, two NADH molecules provide energy to convert pyruvate into fermentation products. By way of the NADH is used, it is rehabilitated back into NAD+. Two molecules of NAD+ are recycled back to glycolysis. Then the glycolysis process could be continuing by the recycled NAD+.


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