Griffith experiment: gene transformation in bacteria
Frederick Griffith (England) in 1928 took an experiment to vaccinate mice against pneumonia by injecting the mice with heat-killed bacteria of encapsulated strain.
For this purpose, he worked with two strains of Streptococcus pneumonia. One is virulent (pathogenic) and other is avirulent. The virulent strain has a polysaccharide capsule in its cell wall. …
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