Antibiotic resistance is increasing day by day over the world and this will cause a dramatic danger to the human civilization. It is now suspected that millions of people will die due to the increasing antibiotic resistance by 2050. Therefore, this increased resistance emphasizes the researchers to find new antimicrobial agents for combating microbial diseases. This article describes 15 antibiotic alternatives some of which may have strong antimicrobial effectiveness against microbial infection.
Antibiotic resistance is now considered to be a great curse to the present world. Researcher suspected that millions of people will die due to the rapid emergence of antibiotic resistance by 2050. There are lots of mechanisms of antibiotic resistance. All the mechanisms of antibiotic resistance can be narrowed into two part; mutation and horizontal gene transfer. In this context, the last mechanism belongs to horizontal gene transfer-mediated resistance and most of the other mechanisms of antibiotic resistance are mutation-mediated.
Phage therapy is the use of phage viruses (bacteriophage) to kill bacterial pathogens as well as drug-resistant bacteria that cause life-threatening infection in the human body. Phage therapy was started in 1919, a few years after the discovery of phage by Frederick Twort (1915) and Felix d’He’relle (1917). But a decade later, due to the discovery of first antibiotic penicillin and emergence of pharmaceutical antibiotics in large quantities, the concept of phage therapy died out by 1940s in west Europe.